Is sertraline safe in early pregnancy?

Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth.

Can sertraline harm a fetus?

Some studies suggest that use of SSRIs, like sertraline, during pregnancy can contribute to pregnancy complications like low birth weight and premature delivery (delivery before 37 weeks of pregnancy).

Can I take sertraline if I’m pregnant?

You may take sertraline during pregnancy if you need it to remain well. Your doctor can explain the risks and the benefits, and will help you decide which treatment is best for you and your baby.

What pregnancy category is sertraline?

Safety of Psychiatric Medications During Pregnancy and Lactation

Drug FDA pregnancy category*
Fluoxetine (Prozac) C
Fluvoxamine (Luvox)‡ C
Paroxetine (Paxil) D
Sertraline (Zoloft) C

Can sertraline cause a miscarriage?

June 2, 2010 — A Canadian study of more than 5,000 women shows an association between taking antidepressants, particularly the selective serotonin reuptake inhibitors (SSRIs) such as Paxil, Prozac, and Zoloft, and an increased risk for miscarriage.

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Is Category C safe during pregnancy?

Category C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Does sertraline cross the placenta?

The lower risk for PPHN associated with sertraline, compared to other SSRIs, is biologically plausible, as sertraline has been shown to cross the placenta at a lower percentage than other SSRIs.

How much sertraline can you take while pregnant?

According to Dr. Ross, a safe and recommended dose of Zoloft begins at 25 mg to 50 mg per day. For moderate to severe depression, Dr. Ross says doses up to 200 mg are deemed safe to use during pregnancy.

What can I take for anxiety when pregnant?

While benzodiazepines are category D, long-term anxiety medications like Prozac and Zoloft are often described as “probably safe.” Tricyclic antidepressants and buspirone may be safe during pregnancy as well.

What medications are not safe during pregnancy?

What medicines should you avoid during pregnancy?

  • Bismuth subsalicylate (such as Pepto-Bismol).
  • Phenylephrine or pseudoephedrine, which are decongestants. …
  • Cough and cold medicines that contain guaifenesin. …
  • Pain medicines like aspirin and ibuprofen (such as Advil and Motrin) and naproxen (such as Aleve).

What antidepressant is safe during pregnancy?

Antidepressants that are considered safer include:

  • Fluoxetine (Prozac, Sarafem)
  • Citalopram (Celexa)
  • Sertraline (Zoloft)
  • Amitriptyline (Elavil)
  • Desipramine (Norpramin)
  • Nortriptyline (Pamelor)
  • Bupropion (Wellbutrin)

24.10.2020

What is pregnancy risk category?

FDA Pregnancy Risk Categories Prior to 2015

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In 1979, the FDA established five letter risk categories – A, B, C, D or X – to indicate the potential of a drug to cause birth defects if used during pregnancy. The categories were determined by assessing the reliability of documentation and the risk to benefit ratio.

What is category B in pregnancy?

Category B drugs include prenatal vitamins, acetaminophen and several other medications used routinely and safely during pregnancy. If there is a clinical need for a Category B drug, it is considered safe to use it.

Can coming off antidepressants cause miscarriage?

Based on these findings, we can conclude that for women taking antidepressants prior to pregnancy, stopping or tapering off the medication does not appreciably affect their risk of miscarriage.

How do I wean myself off of sertraline?

Gradually tapering off Zoloft under a doctor’s supervision can reduce or avoid the symptoms altogether. Usually, sertraline’s dose is gradually reduced over around four weeks. A sample taper schedule is reducing the dose by 50 mg every 5–7 days to a final dose of 25–50 mg before the drug is stopped.

How do antidepressants affect a fetus?

It’s important for a mother and her doctor to know the risks. About 30 percent of babies whose mothers take SSRIs will experience neonatal adaptation syndrome, which can cause increased jitteriness, irritability and respiratory distress (difficulty breathing), among other symptoms.

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